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	<title>lactose &#8211; Terence Eden’s Blog</title>
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	<title>lactose &#8211; Terence Eden’s Blog</title>
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		<title><![CDATA[Can this new probiotic reduce lactose intolerance? ★★★★⯪]]></title>
		<link>https://shkspr.mobi/blog/2023/02/can-this-new-probiotic-reduce-lactose-intolerance/</link>
					<comments>https://shkspr.mobi/blog/2023/02/can-this-new-probiotic-reduce-lactose-intolerance/#comments</comments>
				<dc:creator><![CDATA[Terence Eden]]></dc:creator>
		<pubDate>Wed, 01 Feb 2023 12:34:19 +0000</pubDate>
		<category><![CDATA[health]]></category><category><![CDATA[lactose]]></category><category><![CDATA[vegan]]></category><category><![CDATA[vegetarian]]></category>		<guid isPermaLink="false">https://shkspr.mobi/blog/?p=44150</guid>

					<description><![CDATA[I ordered some pills off the Internet and swallowed them!  What could possibly go wrong?  Let&#039;s get one thing out of the way first. I am not a doctor. I don&#039;t even play one on TV. This blog post is not medical advice.   A few years ago I was suffering from some gastric issues. The doctors had tried several things - including a colonoscopy - but found nothing. At the start of the pandemic, when it …]]></description>
										<content:encoded>&lt;p&gt;I ordered some pills off the Internet and swallowed them!  What could possibly go wrong?&lt;/p&gt;

&lt;p&gt;Let's get one thing out of the way first. I am not a doctor. I don't even play one on TV. This blog post is not medical advice.
&lt;span id="more-44150"&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p&gt;A few years ago I was suffering from some gastric issues. The doctors had tried several things - &lt;a href="https://shkspr.mobi/blog/2020/11/a-year-in-review-2/"&gt;including a colonoscopy&lt;/a&gt; - but found nothing. At the start of the pandemic, when it was impossible to get a GP appointment, I decided to try cutting out dairy.  And that basically solved a lot of issues.  Turns out, I may have age-onset Lactose Intolerance&lt;sup id="fnref:genetics"&gt;&lt;a href="https://shkspr.mobi/blog/2023/02/can-this-new-probiotic-reduce-lactose-intolerance/#fn:genetics" class="footnote-ref" title="THANKS GENETICS!" role="doc-noteref"&gt;0&lt;/a&gt;&lt;/sup&gt;.&lt;/p&gt;

&lt;p&gt;Adjusting to it hasn't been so hard. I was already vegetarian, so switching to being mostly vegan&lt;sup id="fnref:vegan"&gt;&lt;a href="https://shkspr.mobi/blog/2023/02/can-this-new-probiotic-reduce-lactose-intolerance/#fn:vegan" class="footnote-ref" title="I eat honey because I don't think the bees are being exploited." role="doc-noteref"&gt;1&lt;/a&gt;&lt;/sup&gt; was pretty simple.  But I miss proper cheese.&lt;/p&gt;

&lt;p&gt;I occasionally take a Lactayse supplement if I know I can't avoid dairy. But that's a bit of a faff.  And scientists haven't figured out how to permanently cure Lactose Intolerance yet&lt;sup id="fnref:perm"&gt;&lt;a href="https://shkspr.mobi/blog/2023/02/can-this-new-probiotic-reduce-lactose-intolerance/#fn:perm" class="footnote-ref" title="OK, there's this guy who genetically engineered a virus and then infected himself. That seems to work in a sample size of 1. But I'm not brave enough for that." role="doc-noteref"&gt;2&lt;/a&gt;&lt;/sup&gt; - they're too busy trying to cure cancer. Which is reasonable, I suppose.&lt;/p&gt;

&lt;p&gt;And then I discovered &lt;a href="https://www.lactofreedom.com/"&gt;Manzo Pharmaceuticals Lacto-Freedom&lt;/a&gt;.  It's a 1 week course of probiotics which claims to give you several months worth of lactase-producing enzymes. Basically re-colonising your colon to allow you not to shit yourself every time you accidentally look lovingly at a slice of cheese.&lt;/p&gt;

&lt;p&gt;Total cost including shipping from the USA was about £40. Pricey for a small bottle of pills.  But, crucially, do they work?&lt;/p&gt;

&lt;img src="https://shkspr.mobi/blog/wp-content/uploads/2022/11/Lactofreedom-bottle.jpg" alt="A small pharmaceutical bottle. It easily fits in my hand." width="512" height="716" class="aligncenter size-full wp-image-44243"&gt;

&lt;h2 id="the-experiment"&gt;&lt;a href="https://shkspr.mobi/blog/2023/02/can-this-new-probiotic-reduce-lactose-intolerance/#the-experiment"&gt;The experiment&lt;/a&gt;&lt;/h2&gt;

&lt;p&gt;In order to do a proper test, I decided to experiment on myself. I ate some dairy-cheese, a couple of spoonfuls of yoghurt, and washed it down with half-a-pint of semi-skimmed.&lt;/p&gt;

&lt;p&gt;The results were... look, do you want the gory details? There was sound, fury, spasms, bloating and - by the next day - I was literally a kilogram lighter&lt;sup id="fnref:kg"&gt;&lt;a href="https://shkspr.mobi/blog/2023/02/can-this-new-probiotic-reduce-lactose-intolerance/#fn:kg" class="footnote-ref" title="I know you regret reading this post - but I regret nothing!" role="doc-noteref"&gt;3&lt;/a&gt;&lt;/sup&gt;.  So I think it's fairly safe to say that milk doesn't agree with me!&lt;/p&gt;

&lt;h2 id="treatment"&gt;&lt;a href="https://shkspr.mobi/blog/2023/02/can-this-new-probiotic-reduce-lactose-intolerance/#treatment"&gt;Treatment&lt;/a&gt;&lt;/h2&gt;

&lt;p&gt;The probiotics have to be taken on an empty stomach. Either an hour before eating or two hours after. Three times per day. No alcohol consumption - lest you sterilise the little buggers. And, obviously, no antibiotics.&lt;/p&gt;

&lt;p&gt;The pills aren't large:&lt;/p&gt;

&lt;img src="https://shkspr.mobi/blog/wp-content/uploads/2022/11/single-capsule.jpg" alt="A single capsule is a bit over a centimetre long." width="512" height="384" class="aligncenter size-full wp-image-44244"&gt;

&lt;p&gt;21 of those over a week. Then leave it another week to settle down. Then you should be able to consume dairy with impunity&lt;sup id="fnref:impunity"&gt;&lt;a href="https://shkspr.mobi/blog/2023/02/can-this-new-probiotic-reduce-lactose-intolerance/#fn:impunity" class="footnote-ref" title="Best to take it slow at first, OK?" role="doc-noteref"&gt;4&lt;/a&gt;&lt;/sup&gt;.&lt;/p&gt;

&lt;h2 id="the-result"&gt;&lt;a href="https://shkspr.mobi/blog/2023/02/can-this-new-probiotic-reduce-lactose-intolerance/#the-result"&gt;The result&lt;/a&gt;&lt;/h2&gt;

&lt;p&gt;Like any probiotic, they can bubble up inside your guts.  The pack came with a warning that they might cause stomach cramps. For the first couple of days of taking them, I was much more flatulent than usual&lt;sup id="fnref:fart"&gt;&lt;a href="https://shkspr.mobi/blog/2023/02/can-this-new-probiotic-reduce-lactose-intolerance/#fn:fart" class="footnote-ref" title="It was almost musical..." role="doc-noteref"&gt;5&lt;/a&gt;&lt;/sup&gt;. It took a few days for things to calm down&lt;sup id="fnref:turbine"&gt;&lt;a href="https://shkspr.mobi/blog/2023/02/can-this-new-probiotic-reduce-lactose-intolerance/#fn:turbine" class="footnote-ref" title="Honestly, if you'd stuck a wind turbine near my arse it could have powered half the street." role="doc-noteref"&gt;6&lt;/a&gt;&lt;/sup&gt;.&lt;/p&gt;

&lt;p&gt;I took all 21 over a week. Waited a few days. Then poured cow's milk all over my cereal.  And...&lt;/p&gt;

&lt;p&gt;…Nothing. My stomach gave a few little rumbles throughout the day. But I never experienced that &lt;strong&gt;it's happening&lt;/strong&gt; feeling which will be common to so many of my LI friends.  The little critters in my intestines chomped away on the lactose. I felt a little bloated, but nothing like I usually do.&lt;/p&gt;

&lt;p&gt;I didn't go overboard with dairy&lt;sup id="fnref:cheese"&gt;&lt;a href="https://shkspr.mobi/blog/2023/02/can-this-new-probiotic-reduce-lactose-intolerance/#fn:cheese" class="footnote-ref" title="I wanted to eat my bodyweight in Stinking Bishop." role="doc-noteref"&gt;7&lt;/a&gt;&lt;/sup&gt; over the next few days. A scrap of cheese, milk on my cereal, the occasional snaffle of chocolate. It all seemed to go just fine.&lt;/p&gt;

&lt;p&gt;The "protection" is supposed to last for around 3 months. Is £160 per year a good deal in order to feel confident that you're not going to have an embarrassing moment if you accidentally eat an entire Edam? You tell me.&lt;/p&gt;

&lt;h2 id="how-does-it-work"&gt;&lt;a href="https://shkspr.mobi/blog/2023/02/can-this-new-probiotic-reduce-lactose-intolerance/#how-does-it-work"&gt;How does it work?&lt;/a&gt;&lt;/h2&gt;

&lt;p&gt;SCIENCE! A per &lt;a href="https://pubchem.ncbi.nlm.nih.gov/patent/US-8236297-B2"&gt;their patent&lt;/a&gt;, they genetically engineered &lt;i lang="la"&gt;L. acidophilus MPH734&lt;/i&gt;. They tested its effectiveness &lt;a href="https://www.lactofreedom.com/lacto-freedom-info"&gt;on rats &lt;em&gt;and&lt;/em&gt; humans&lt;/a&gt;.&lt;/p&gt;

&lt;p&gt;But, it's important to note the disclaimer on their website:&lt;/p&gt;

&lt;blockquote&gt;&lt;p&gt;These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.&lt;/p&gt;&lt;/blockquote&gt;

&lt;p&gt;There is a &lt;a href="https://clinicaltrials.gov/ct2/show/NCT04531033"&gt;clinical trial record&lt;/a&gt; - but no results have been published.&lt;/p&gt;

&lt;h2 id="should-i-take-it"&gt;&lt;a href="https://shkspr.mobi/blog/2023/02/can-this-new-probiotic-reduce-lactose-intolerance/#should-i-take-it"&gt;Should I take it?&lt;/a&gt;&lt;/h2&gt;

&lt;p&gt;I am not a doctor. I cannot give medical advice. I am not being paid to promote these. The pills haven't been officially tested in the UK, as far as I know.&lt;/p&gt;

&lt;p&gt;But, reporting on this study of one person, these &lt;em&gt;seem&lt;/em&gt; to work.  I haven't tried stuffing my face with a thousand kilos of cheese - that's probably enough to overwhelm anyone's guts. But for managing the odd pizza, or cheese on crackers, or a packet of crisps inexplicably bulked up with milk powder - it's pretty good!&lt;/p&gt;

&lt;div id="footnotes" role="doc-endnotes"&gt;
&lt;hr aria-label="Footnotes"&gt;
&lt;ol start="0"&gt;

&lt;li id="fn:genetics"&gt;
&lt;p&gt;THANKS GENETICS!&amp;nbsp;&lt;a href="https://shkspr.mobi/blog/2023/02/can-this-new-probiotic-reduce-lactose-intolerance/#fnref:genetics" class="footnote-backref" role="doc-backlink"&gt;↩︎&lt;/a&gt;&lt;/p&gt;
&lt;/li&gt;

&lt;li id="fn:vegan"&gt;
&lt;p&gt;I eat honey because I don't think the bees are being exploited.&amp;nbsp;&lt;a href="https://shkspr.mobi/blog/2023/02/can-this-new-probiotic-reduce-lactose-intolerance/#fnref:vegan" class="footnote-backref" role="doc-backlink"&gt;↩︎&lt;/a&gt;&lt;/p&gt;
&lt;/li&gt;

&lt;li id="fn:perm"&gt;
&lt;p&gt;OK, there's this guy who &lt;a href="https://www.youtube.com/watch?v=aoczYXJeMY4"&gt;&lt;em&gt;genetically engineered a virus and then infected himself&lt;/em&gt;&lt;/a&gt;. That seems to work in a sample size of 1. But I'm not brave enough for that.&amp;nbsp;&lt;a href="https://shkspr.mobi/blog/2023/02/can-this-new-probiotic-reduce-lactose-intolerance/#fnref:perm" class="footnote-backref" role="doc-backlink"&gt;↩︎&lt;/a&gt;&lt;/p&gt;
&lt;/li&gt;

&lt;li id="fn:kg"&gt;
&lt;p&gt;I know you regret reading this post - but I regret nothing!&amp;nbsp;&lt;a href="https://shkspr.mobi/blog/2023/02/can-this-new-probiotic-reduce-lactose-intolerance/#fnref:kg" class="footnote-backref" role="doc-backlink"&gt;↩︎&lt;/a&gt;&lt;/p&gt;
&lt;/li&gt;

&lt;li id="fn:impunity"&gt;
&lt;p&gt;Best to take it slow at first, OK?&amp;nbsp;&lt;a href="https://shkspr.mobi/blog/2023/02/can-this-new-probiotic-reduce-lactose-intolerance/#fnref:impunity" class="footnote-backref" role="doc-backlink"&gt;↩︎&lt;/a&gt;&lt;/p&gt;
&lt;/li&gt;

&lt;li id="fn:fart"&gt;
&lt;p&gt;It was almost musical...&amp;nbsp;&lt;a href="https://shkspr.mobi/blog/2023/02/can-this-new-probiotic-reduce-lactose-intolerance/#fnref:fart" class="footnote-backref" role="doc-backlink"&gt;↩︎&lt;/a&gt;&lt;/p&gt;
&lt;/li&gt;

&lt;li id="fn:turbine"&gt;
&lt;p&gt;Honestly, if you'd stuck a wind turbine near my arse it could have powered half the street.&amp;nbsp;&lt;a href="https://shkspr.mobi/blog/2023/02/can-this-new-probiotic-reduce-lactose-intolerance/#fnref:turbine" class="footnote-backref" role="doc-backlink"&gt;↩︎&lt;/a&gt;&lt;/p&gt;
&lt;/li&gt;

&lt;li id="fn:cheese"&gt;
&lt;p&gt;I wanted to eat my bodyweight in Stinking Bishop.&amp;nbsp;&lt;a href="https://shkspr.mobi/blog/2023/02/can-this-new-probiotic-reduce-lactose-intolerance/#fnref:cheese" class="footnote-backref" role="doc-backlink"&gt;↩︎&lt;/a&gt;&lt;/p&gt;
&lt;/li&gt;

&lt;/ol&gt;
&lt;/div&gt;
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