Here's a quick article about pixel alignment: http://likethought.com/lockfocus/2009/10/pixel-aligning/

It seems like you're talking about different things, he's pointing out a technical problem (do my elements which should line up with pixel boundaries line up with the pixels?) while you're asking a higher level question (would someone be able to use the software looking like this?) It's easy to see how there could be a miss-match when comparing the answers to those two questions.