Hi Terry.
This must be one of the most epic business trips ever! I am hugely impressed you managed to organise this and look forward to seeing some cracking photos when you return.
This advice is provided from myself as a regular visit to South Africa and from my wife, who as you know grew up there:
If you have any spare time in Jo'burg and you want to get a sense of how things feel from the township perspective, visit Soweto. There are lots of official tours available and several interesting sites to see, including the World Cup stadium, one of Madela's old homes, the apartheid museum and the Hector Pietersen musuem. I found it to be an enlightening and positive place and one that shows the visitor a totally different side of SA. This can all be done in about half a day (at a push). If you have more spare time then get out of town and find a game reserve.
As it is winter in SA you may need to wrap up warm on some days. Frosts are not uncommon in Jo'burg at this time of the year and Cape Town can get quite wet.
Steve is absolutely right about security - but try not to let it get to you. It's all common sense really: seek local advice, keep your flashy phones out of sight (preferably locked away in the hotel), avoid public transport and do not drive at night in central Jo'burg or Pretoria. I am advised that Cape Town is more laid back and some of this advice may not apply there.
Have a great trip and stay safe!